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1

Engineered protein scaffolds for molecular recognition

Journal:

Journal of Molecular Recognition

Year:

2000

Language:

english

File:

PDF, 556 KB

english, 2000

2

Construction of an Artificial Receptor Protein (“Anticalin”) Based on the Human Apolipoprotein D

Martin Vogt, Arne Skerra

Journal:

Year:

2004

Language:

english

File:

PDF, 232 KB

english, 2004

3

Engineered protein scaffolds as next-generation antibody therapeutics

Michaela Gebauer, Arne Skerra

Journal:

Current Opinion in Chemical Biology

Year:

2009

Language:

english

File:

PDF, 366 KB

english, 2009

4

Assembly of a functional immunoglobulin Fv fragment in Escherichia coli

Skerra, A, Pluckthun, A

Journal:

Year:

1988

Language:

english

File:

PDF, 1.17 MB

english, 1988

5

[Methods in Enzymology] Applications of Chimeric Genes and Hybrid Proteins Part A: Gene Expression and Protein Purification Volume 326 || [18] Use of the Strep- tag and streptavidin for detection and purification of recombinant proteins

Year:

2000

Language:

english

File:

PDF, 4.49 MB

english, 2000

6

Anticalins directed against vascular endothelial growth factor receptor 3 (VEGFR-3) with picomolar affinities show potential for medical therapy and in vivo imaging

Richter, Antonia, Skerra, Arne

Journal:

Biological Chemistry

Year:

2017

Language:

english

File:

PDF, 1.42 MB

english, 2017

7

PASylation®: A versatile technology to extend drug delivery

Binder, Uli, Skerra, Arne

Journal:

Current Opinion in Colloid & Interface Science

Year:

2017

Language:

english

File:

PDF, 548 KB

english, 2017

8

Rational Design of an Anticalin-Type Sugar-Binding Protein Using a Genetically Encoded Boronate Side Chain

Edwardraja, Selvakumar, Eichinger, Andreas, Theobald, Ina, Sommer, Carina Andrea, Reichert, Andreas J., Skerra, Arne

Journal:

ACS Synthetic Biology

Year:

2017

Language:

english

File:

PDF, 15.42 MB

english, 2017

9

Fixation of gaseous CO2 by reversing a decarboxylase for the biocatalytic synthesis of the essential amino acid l-methionine

Martin, Julia, Eisoldt, Lukas, Skerra, Arne

Journal:

Nature Catalysis

Year:

2018

Language:

english

File:

PDF, 1.75 MB

english, 2018

10

Engineered Protein Scaffolds as Next-Generation Therapeutics

Gebauer, Michaela, Skerra, Arne

Journal:

Annual Review of Pharmacology

Year:

2020

File:

PDF, 3.17 MB

2020

11

Bacterially produced apolipoprotein D binds progesterone and arachidonic acid, but not bilirubin or E-3M2H

Martin Vogt, Arne Skerra

Journal:

Journal of Molecular Recognition

Year:

2001

Language:

english

File:

PDF, 4.23 MB

english, 2001

12

Über die Analyse der Photosynthese mit Blitzlicht

H. T. Witt, B. Rumberg, P. Schmidt-Mende, U. Siggel, B. Skerra, J. Vater, J. Weikard

Journal:

Angewandte Chemie

Year:

1965

Language:

german

File:

PDF, 2.00 MB

german, 1965

13

On the Analysis of Photosynthesis by Flashlight Techniques

H. T. Witt, B. Rumberg, P. Schmidt-Mende, U. Siggel, B. Skerra, J. Vater, J. Weikard

Journal:

Angewandte Chemie International Edition

Year:

1965

Language:

english

File:

PDF, 1.84 MB

english, 1965

14

Biochemistry in 2004

Arne Skerra, Andreas Eichinger

Journal:

Year:

2005

File:

PDF, 8 KB

2005

15

Wissenschaft aktuell

Arne Skerra, Bernhard Dick, Wolfgang Tremel

Journal:

Chemie in unserer Zeit

Year:

1997

Language:

german

File:

PDF, 1.16 MB

german, 1997

16

Amination of Ketones by Employing Two New (S)-Selective ω-Transaminases and the His-Tagged ω-TA from Vibrio fluvialis

Francesco G. Mutti, Christine S. Fuchs, Desiree Pressnitz, Nikolaus G. Turrini, Johann H. Sattler, Alexandra Lerchner, Arne Skerra, Wolfgang Kroutil

Journal:

European Journal of Organic Chemistry

Year:

2012

Language:

english

File:

PDF, 194 KB

english, 2012

17

Epitope mapping of the neuronal growth inhibitor Nogo-A for the Nogo receptor and the cognate monoclonal antibody IN-1 by means of the SPOT technique

Hilke Zander, Ulrich Reineke, Jens Schneider-Mergener, Arne Skerra

Journal:

Journal of Molecular Recognition

Year:

2007

Language:

english

File:

PDF, 371 KB

english, 2007

18

Filter screening of antibody Fab fragments secreted from individual bacterial colonies: Specific detection of antigen binding with a two-membrane system

Arne Skerra, Martin L. Dreher, Greg Winter

Journal:

Analytical Biochemistry

Year:

1991

Language:

english

File:

PDF, 1.83 MB

english, 1991

19

Single-step purification of a bacterially expressed antibody Fv fragment by immobilized metal affinity chromatography in the presence of betaine

Lars-Oliver Essen, Arne Skerra

Journal:

Journal of Chromatography A

Year:

1993

Language:

english

File:

PDF, 1.73 MB

english, 1993

20

One-step affinity purification of bacterially produced proteins by means of the “Strep tag” and immobilized recombinant core streptavidin

Thomas G.M. Schmidt, Arne Skerra

Journal:

Journal of Chromatography A

Year:

1994

Language:

english

File:

PDF, 1.08 MB

english, 1994

21

Bacterial expression of immunoglobulin fragments

Journal:

Current Opinion in Immunology

Year:

1993

Language:

english

File:

PDF, 1.05 MB

english, 1993

22

Comparative ligand-binding analysis of ten human lipocalins

Daniel A. Breustedt, Dorian L. Schönfeld, Arne Skerra

Journal:

Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics

Year:

2006

Language:

english

File:

PDF, 524 KB

english, 2006

23

Imitating the humoral immune response

Journal:

Current Opinion in Chemical Biology

Year:

2003

Language:

english

File:

PDF, 338 KB

english, 2003

24

Generation of anticalins with specificity for a nonsymmetric phthalic acid ester

Josep V Mercader, Arne Skerra

Journal:

Analytical Biochemistry

Year:

2002

Language:

english

File:

PDF, 260 KB

english, 2002

25

Tuning ligand affinity, specificity, and folding stability of an engineered lipocalin variant — a so-called ‘anticalin’ — using a molecular random approach

Steffen Schlehuber, Arne Skerra

Journal:

Biophysical Chemistry

Year:

2002

Language:

english

File:

PDF, 753 KB

english, 2002

26

Immobilization of histidine-tagged proteins on gold surfaces using chelator thioalkanes

Dietmar Kröger, Martha Liley, Wolfram Schiweck, Arne Skerra, Horst Vogel

Journal:

Biosensors and Bioelectronics

Year:

1999

Language:

english

File:

PDF, 143 KB

english, 1999

27

Applications of a peptide ligand for streptavidin: the Strep-tag

Arne Skerra, Thomas G.M Schmidt

Journal:

Biomolecular Engineering

Year:

1999

Language:

english

File:

PDF, 314 KB

english, 1999

28

A Zn(II)-binding site engineered into retinol-binding protein exhibits metal-ion specificity and allows highly efficient affinity purification with a newly designed metal ligand

AndréM. Schmidt, Holger N. Müller, Arne Skerra

Journal:

Chemistry & Biology

Year:

1996

Language:

english

File:

PDF, 1.56 MB

english, 1996

29

Identification of potential substrate proteins for the periplasmic Escherichia coli chaperone Skp

Svenja Jarchow, Carsten Lück, Angelika Görg, Arne Skerra

Journal:

Year:

2008

Language:

english

File:

PDF, 376 KB

english, 2008

30

Crystal structure of the sensory domain of Escherichia coli CadC, a member of the ToxR-like protein family

Andreas Eichinger, Ina Haneburger, Christiane Koller, Kirsten Jung, Arne Skerra

Journal:

Protein Science

Year:

2011

Language:

english

File:

PDF, 1.03 MB

english, 2011

31

Crystallographic analysis of an “anticalin” with tailored specificity for fluorescein reveals high structural plasticity of the lipocalin loop region

Ingo P. Korndörfer, Gerald Beste, Arne Skerra

Journal:

Proteins: Structure, Function, and Bioinformatics

Year:

2003

Language:

english

File:

PDF, 526 KB

english, 2003

32

The structure of the anti-c-myc antibody 9E10 Fab fragment/epitope peptide complex reveals a novel binding mode dominated by the heavy chain hypervariable loops

Norbert Krauß, Helga Wessner, Karin Welfle, Heinz Welfle, Christa Scholz, Martina Seifert, Kristina Zubow, Jacqueline Aÿ, Michael Hahn, Patrick Scheerer, Arne Skerra, Wolfgang Höhne

Journal:

Proteins: Structure, Function, and Bioinformatics

Year:

2008

Language:

english

File:

PDF, 950 KB

english, 2008

33

Fermenter production of an artificial fab fragment, rationally designed for the antigen cystatin, and its optimized crystallization through constant domain shuffling

Wolfram Schiweck, Prof. Dr. Arne Skerra

Journal:

Proteins: Structure, Function, and Bioinformatics

Year:

1995

Language:

english

File:

PDF, 628 KB

english, 1995

34

Regeneration of Auditory Nerve Following Complete Sectioning and Intrathecal Application of the IN-1 Antibody

M. Tatagiba, S. Rosahl, A. Gharabaghi, U. Blömer, A. Brandis, A. Skerra, M. Samii, M. E. Schwab

Journal:

Acta Neurochirurgica

Year:

2002

Language:

english

File:

PDF, 199 KB

english, 2002

35

Alternative non-antibody scaffolds for molecular recognition

Journal:

Current Opinion in Biotechnology

Year:

2007

Language:

english

File:

PDF, 183 KB

english, 2007

36

Interferon-γ Regulates Intestinal Epithelial Homeostasis through Converging β-Catenin Signaling Pathways

Porfirio Nava, Stefan Koch, Mike G. Laukoetter, Winston Y. Lee, Keli Kolegraff, Christopher T. Capaldo, Neal Beeman, Caroline Addis, Kirsten Gerner-Smidt, Irmgard Neumaier, Arne Skerra, Linheng Li, Ch

Journal:

Year:

2010

Language:

english

File:

PDF, 1.68 MB

english, 2010

37

A generic strategy for subcloning antibody variable regions from the scFv phage display vector pCANTAB 5 E into pASK85 permits the economical production of Fab fragments and leads to improved recombinant immunoglobulin stability

Karl Kramer, Markus Fiedler, Arne Skerra, Bertold Hock

Journal:

Biosensors and Bioelectronics

Year:

2002

Language:

english

File:

PDF, 380 KB

english, 2002

38

Sulfite oxidase controls sulfur metabolism under SO2 exposure in Arabidopsis thaliana

DÖRTE RANDEWIG, DOMENICA HAMISCH, CORNELIA HERSCHBACH, MONIKA EIBLMEIER, CHRISTIAN GEHL, JENS JURGELEIT, JESSICA SKERRA, RALF R. MENDEL, HEINZ RENNENBERG, ROBERT HÄNSCH

Journal:

Plant, Cell & Environment

Year:

2012

Language:

english

File:

PDF, 9.85 MB

english, 2012

39

Biochemical characterization of the recombinant human Nogo-A ectodomain

Hilke Zander, Eva Hettich, Kathrin Greiff, Lorenz Chatwell, Arne Skerra

Journal:

Year:

2007

Language:

english

File:

PDF, 379 KB

english, 2007

40

Alternative binding proteins get mature: Rivalling antibodies

Harald Kolmar, Arne Skerra

Journal:

Year:

2008

Language:

english

File:

PDF, 54 KB

english, 2008

41

Alternative binding proteins: Anticalins – harnessing the structural plasticity of the lipocalin ligand pocket to engineer novel binding activities

Journal:

Year:

2008

Language:

english

File:

PDF, 298 KB

english, 2008

42

Engineered Fv Fragments as a Tool for the One-Step Purification of Integral Multisubunit Membrane Protein Complexes

Kleymann, Gerald, Ostermeier, Christian, Ludwig, Bernd, Skerra, Arne, Michel, Hartmut

Journal:

Year:

1995

File:

PDF, 725 KB

1995

43

The Strep-tag system for one-step purification and high-affinity detection or capturing of proteins

Schmidt, Thomas GM, Skerra, Arne

Journal:

Nature Protocols

Year:

2007

Language:

english

File:

PDF, 293 KB

english, 2007

44

Structure of the periplasmic chaperone Skp suggests functional similarity with cytosolic chaperones despite differing architecture

Korndörfer, Ingo P, Dommel, Monica K, Skerra, Arne

Journal:

Nature Structural and Molecular Biology

Year:

2004

Language:

english

File:

PDF, 1.09 MB

english, 2004

45

Anticalins as an alternative to antibody technology

Schlehuber, Steffen, Skerra, Arne

Journal:

Expert Opinion on Biological Therapy

Year:

2005

Language:

english

File:

PDF, 1.32 MB

english, 2005

46

Solubility engineering and crystallization of human apolipoprotein D

Amber Nasreen, Martin Vogt, Hyun Jin Kim, Andreas Eichinger, Arne Skerra

Journal:

Protein Science

Year:

2006

Language:

english

File:

PDF, 448 KB

english, 2006

47

Improved affinity of engineered streptavidin for the Strep-tag II peptide is due to a fixed open conformation of the lid-like loop at the binding site

Ingo P. Korndörfer, Arne Skerra

Journal:

Protein Science

Year:

2002

Language:

english

File:

PDF, 3.88 MB

english, 2002

48

Biosynthesis of a Fluorescent Protein with Extreme Pseudo-Stokes Shift by Introducing a Genetically Encoded Non-Natural Amino Acid outside the Fluorophore

Kuhn, Sebastian M., Rubini, Marina, Müller, Michael A., Skerra, Arne

Journal:

Journal of the American Chemical Society

Year:

2011

Language:

english

File:

PDF, 1.94 MB

english, 2011

49

DNA vaccination efficiently induces antibodies to Nogo-A and does not exacerbate experimental autoimmune encephalomyelitis

Carole Bourquin, Marjan E. van der Haar, David Anz, Nadja Sandholzer, Irmgard Neumaier, Stefan Endres, Arne Skerra, Martin E. Schwab, Christopher Linington

Journal:

European Journal of Pharmacology

Year:

2008

Language:

english

File:

PDF, 1.32 MB

english, 2008

50

Binding proteins from alternative scaffolds

Per-Åke Nygren, Arne Skerra

Journal:

Journal of Immunological Methods

Year:

2004

Language:

english

File:

PDF, 340 KB

english, 2004

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